SEGi's main campus, in Kota Damansara, houses several faculties including Business, Technology and Innovation, Creative Arts and Design, and Dentistry. The most recently built facility, Kota Damansara MRT Station, provides access to students from Petaling Jaya and Kuala Lumpur.

The campus has facilities including an academic library and swimming pool. It can accommodate up to 12,000 students. An extension building known as SEGi Tower is a few hundred metres away to accommodate an additional 6,000 students.

SEGi University has been recognised as a QS 5 Star Plus institution according to the QS World University Rankings 2022. SEGi University obtained 5 Stars ratings in eight evaluations: Teaching, Internationalisation, Online Learning, Arts & Culture, Employability, Academic Development, Inclusiveness, and Specialist Criteria: Bachelor of Medicine and Bachelor of Surgery (MBBS). This prestigious rating places SEGi University among the top 21 universities globally.